7-Amino-4-methylcoumarin-3-acetic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

7-Amino-4-methylcoumarin 比 GD(4)K-NA 更适合作为肠肽酶的底物。

7-Amino-4-methylcoumarin is more suitable as a substrate for enteropeptidase than GD(4)K-NA.(In Vitro):In this study, we used shift in the emission spectrum of GD(4)K-conjugated 7-Amino-4-methylcoumarin (GD(4)K-AMC) as a fluorogenic method to measure enteropeptidase activity. The kinetic analysis revealed that enteropeptidase has a K(M) of 0.025 mM and a k(cat) of 65 sec(-1) for 7-Amino-4-methylcoumarin, whereas it has a K(M) of 0.5 to 0.6 mM and a k(cat) of 25 sec(-1) for GD(4)K-NA. The optimum pH of 7-Amino-4-methylcoumarin hydrolysis was pH 8.0.

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7-Amino-4-methylcoumarin

Others

Other Targets

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106562-32-7

233.223

C12H11NO4

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (535.97 mM)

Cc1c(CC(O)=O)c(=O)oc2cc(N)ccc12

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(-20℃)

With Ice Pack

≥ 2 years